1-Boc-4-(aminomethyl)piperidine → tert-butyl 4-({[4-[2-(difluoromethyl)-4-methoxy-1H-benzimidazol-1-yl]-6-(4-morpholinyl)-1,3,5-triazin-2-yl]amino}methyl)-1-piperidinecarboxylate

HRID 215557

Reaction equation

HRID 215557 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[n:14]2[c:15]([CH:25]([F:26])[F:27])[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][c:22]3[O:23][CH3:24])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1.[NH2:28][CH2:29][CH:30]1[CH2:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]1>>[c:2]1([NH:28][CH2:29][CH:30]2[CH2:31][CH2:32][N:33]([C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[CH2:34][CH2:35]2)[n:3][c:4](-[n:14]2[c:15]([CH:25]([F:26])[F:27])[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][c:22]3[O:23][CH3:24])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1

Participants

3

Reactant 2

HCID 7368171-Boc-4-(aminomethyl)piperidineHCID 534881021-[4-Chloro-6-(morpholin-4-yl)-1,3,5-triazin-2-yl]-2-(difluoromethyl)-4-methoxy-1H-benzimidazole

Product 1

HCID 67545869tert-butyl 4-({[4-[2-(difluoromethyl)-4-methoxy-1H-benzimidazol-1-yl]-6-(4-morpholinyl)-1,3,5-triazin-2-yl]amino}methyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-7355f9ba6b434e58a505594ebe07f9b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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