7-Amino-2-methyl-4-(morpholin-4-yl)-2,3-dihydro-1H-isoindol-1-one → Diethyl (4-{[4-{[2-methyl-7-(morpholin-4-yl)-3-oxo-2,3-dihydro-1H-isoindol-4-yl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[cH:14][cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:28][c:29]1[cH:30][cH:31][c:32]([N:40]2[CH2:41][CH2:42][O:43][CH2:44][CH2:45]2)[c:33]2[c:37]1[C:36](=[O:38])[N:35]([CH3:39])[CH2:34]2>>[c:2]1([NH:28][c:29]2[cH:30][cH:31][c:32]([N:40]3[CH2:41][CH2:42][O:43][CH2:44][CH2:45]3)[c:33]3[c:37]2[C:36](=[O:38])[N:35]([CH3:39])[CH2:34]3)[n:3][c:4]([NH:12][c:13]2[cH:14][cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ebc6f1a70df3492a97ce0388e517a745
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)