HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 2-pyrimidinamine, N-(3-chlorophenyl)-4-(4-pyridinyl)- | HCID 644214 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine | HCID 19689585 | — |
Reaction Steps
10 g (35.4 mmol) of N-(3-chloro-phenyl)-4-(4-pyridyl)-2-pyrimidineamine and 11.1 g (35.4 mmol) of m-chloroperbenzoic acid are stirred for 5 h at RT in 500 ml of methylene chloride. Concentration and crystallisation (acetic acid) of the residue give N-(3-chloro-phenyl)-4-(N-oxido4-pyridyl)-2-pyrimidineamine; m.p. 274°-275°, Rf =0.6 (methylene chloride:methanol=9:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728708 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-a39fc3b67bbd45ff88d29b84e47f577f |
| Source note | uspto-grants-1998_03 |