Carbonate Ion → 6-(3-Fluorophenyl)-5-pyridin-4-ylpyrazin-2-amine

HRID 2162728Notes

Reaction equation

HRID 2162728 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([NH2:15])[n:6][c:7]1-[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1.[C:31](=[O:32])([O-:33])[O-:34].[CH3:16][C:17]1([CH3:18])[C:19]([CH3:20])([CH3:21])[O:22][B:23]([c:24]2[cH:25][cH:26][n:27][cH:28][cH:29]2)[O:30]1.[Cs+:35].[Cs+:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[c:2]1(-[c:24]2[cH:25][cH:26][n:27][cH:28][cH:29]2)[n:3][cH:4][c:5]([NH2:15])[n:6][c:7]1-[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1

Participants

6

Reactant 5

HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 27346484-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 594576145-Bromo-6-(3-fluorophenyl)pyrazin-2-amine

Product 1

HCID 160715396-(3-Fluorophenyl)-5-pyridin-4-ylpyrazin-2-amine

Sources & evidence

ORD record
ord-9c1107a5a601400799b2f81d98d803ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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