Hydroxylamine, O-ethyl- → HCID 135999353, compound
Reaction equation
[OH:1][C:2]1[CH2:7][CH:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)[CH2:5][C:4](=[O:16])[C:3]=1[C:17](=O)[CH2:18][CH3:19].[CH2:21]([O:23][NH2:24])[CH3:22]>C(O)C>[CH2:21]([O:23][N:24]=[C:17]([C:3]1[C:4](=[O:16])[CH2:5][CH:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)[CH2:7][C:2]=1[OH:1])[CH2:18][CH3:19])[CH3:22]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Into 20 ml of ethanol was dissolved 2.9 g of 3-hydroxy-5-(4-methylthiophenyl)-2-propionyl-2-cyclohexen-1-one and to the solution was added 0.8 g of ethoxyamine. The mixture was kept for 15 hours at room temperature and it was poured into ice water. The crystal sedimented was collected with a filtering step and recrystallized with methanol. Thus, 3.1 g of colorless objective crystals having a melting point of 83°-84° C. was obtained.