Fluorine → HCID 20497530, compound
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][C:11](=[O:16])[C:12]([O:14][CH3:15])=[O:13])([O-:3])=[O:2].[F:17]F>C(#N)C>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:10]([F:17])[C:11](=[O:16])[C:12]([O:14][CH3:15])=[O:13])([O-:3])=[O:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
In the same manner as in Example 1, methyl 3-(2-nitrophenyl)pyruvate (2.23 g; 10 mmol) is dissolved in acetonitrile (50 g) and reacted with fluorine. By distilling off the solvent under reduced pressure, there is obtained a crude product, whicch is rectified to give methyl 3-(2-nitrophenyl)-3-fluoropyruvate.
Workup
- distillationBy distilling off the solvent under reduced pressure
- customthere is obtained a crude product, whicch
Sources & evidence
- ORD record
- ord-5a24c407c90a4180b97a6c65afe37a54
- Source dataset
- uspto-grants-1983_06
- Patent number
- US04390702
Reaction notes
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