(1-Phenylcyclopentyl)methanol → 1-(p-Chlorophenyl)cyclopentanemethanol

HRID 2169152

Reaction equation

HRID 2169152 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([CH:13]=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C1(C2(CO)CCCC2)C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:13][OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 123544(1-Phenylcyclopentyl)methanolHCID 214680001-(4-Chlorophenyl)-cyclopentanecarbaldehyde

Product 1

HCID 27240171-(p-Chlorophenyl)cyclopentanemethanolYield 37.52%

Procedure

[1-(4-chlorophenyl)-cyclopentyl]-methanol (23-02) (25 g, 37.52%) was synthesized from 1-(4-chlorophenyl)-cyclopentanecarbaldehyde (22-02) (66 g, 317.3 mmol) as a colourless liquid following the procedure as described for (1-phenyl-cyclopentyl)-methanol (23-01).

Sources & evidence

ORD record
ord-97402fbe3fad4caa8f7d8dbad8ea6da8
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Linked notes

Loading…