Suberic acid → Oxonane-2,9-dione

HRID 217095

Reaction equation

HRID 217095 reaction equation
[C:1]([OH:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=O>CC(OC(C)=O)=O>[O:12]1[C:1](=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]1=[O:10]

Participants

3

Reactant 1

HCID 10457Suberic acid

Product 1

HCID 9543534Oxonane-2,9-dione

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

Under N2 atmosphere 50 g suberic acid and 100 ml acetanhydride were refluxed for 2 hours. The solvent was evaporated and 200 ml acetonitrile were added to the residue and the mixture was kept in a freezer over night. Then the mixture was fritted and the resulting residue was washed with 50 ml acetonitrile and dried.

Workup

  1. customThe solvent was evaporated
  2. addition200 ml acetonitrile were added to the residue
  3. waitthe mixture was kept in a freezer over night
  4. washthe resulting residue was washed with 50 ml acetonitrile
  5. customdried

Sources & evidence

ORD record
ord-d4634b1c94844c949baa8b06a896ae0b
Source dataset
uspto-grants-2012_06
Patent number
US08193246B2

Linked notes

Loading…