HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-Carbamyl-6-Hydroxybenzothiazole Dimethylphosphate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phosphorochloridic acid, dimethyl ester | HCID 101863 | — |
| Reactant | 2-Benzothiazolecarboxamide, 6-hydroxy- | HCID 9838911 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Carbamyl-6-Hydroxybenzothiazole Dimethylphosphate | HCID 86748732 | — |
Reaction Steps
Three grams (0.015moles) of 2-carbamyl-6-hydroxybenzothiazole (ABT) was dissolved in 30 mLs of THF. Then 1.72 g (0.017 moles) triethylamine was added to the stirring reaction solution, followed immediately by the addition over 5 minutes of 2.6 g (0.018 moles) of dimethylchlorophosphate dissolved in 7 mLs of THF. This solution was stirred for 72 hours at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05424440 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-34a06c3811de450caff1736c91de2d1f |
| Source note | uspto-grants-1995_06 |