Fumaric Acid → Aliskiren hemifumarate
Reaction equation
[CH3:1][CH:2]([C@H:4]([CH2:20][C@H:21]([NH2:39])[C@@H:22]([OH:38])[CH2:23][C@H:24]([C:28]([NH:30][CH2:31][C:32]([C:35]([NH2:37])=[O:36])([CH3:34])[CH3:33])=[O:29])[CH:25]([CH3:27])[CH3:26])[CH2:5][C:6]1[CH:7]=[CH:8][C:9]([O:18][CH3:19])=[C:10]([O:12][CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH:11]=1)[CH3:3].[C:40]([OH:47])(=[O:46])/[CH:41]=[CH:42]/[C:43]([OH:45])=[O:44]>C(O)C.C(#N)C>[CH3:3][CH:2]([C@H:4]([CH2:20][C@H:21]([NH2:39])[C@@H:22]([OH:38])[CH2:23][C@H:24]([C:28]([NH:30][CH2:31][C:32]([C:35]([NH2:37])=[O:36])([CH3:33])[CH3:34])=[O:29])[CH:25]([CH3:26])[CH3:27])[CH2:5][C:6]1[CH:7]=[CH:8][C:9]([O:18][CH3:19])=[C:10]([O:12][CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH:11]=1)[CH3:1].[CH3:3][CH:2]([C@H:4]([CH2:20][C@H:21]([NH2:39])[C@@H:22]([OH:38])[CH2:23][C@H:24]([C:28]([NH:30][CH2:31][C:32]([C:35]([NH2:37])=[O:36])([CH3:33])[CH3:34])=[O:29])[CH:25]([CH3:26])[CH3:27])[CH2:5][C:6]1[CH:7]=[CH:8][C:9]([O:18][CH3:19])=[C:10]([O:12][CH2:13][CH2:14][CH2:15][O:16][CH3:17])[CH:11]=1)[CH3:1].[CH:41](/[C:40]([OH:47])=[O:46])=[CH:42]\[C:43]([OH:45])=[O:44]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 52.5 °C