2-Amino-4-methylpyridine-3-carboxylic acid → HCID 90412569, compound

Reaction equation

N[C:2]1N=C(C(O)=O)C(C)=C[CH:3]=1.[NH2:12][C:13]1[N:21]=[CH:20][CH:19]=[C:18]([CH3:22])[C:14]=1[C:15]([OH:17])=[O:16]>>[CH3:22][C:18]1[CH:19]=[CH:20][N:21]2[CH:2]=[CH:3][N:12]=[C:13]2[C:14]=1[C:15]([OH:17])=[O:16]

Participants

Reactant 2

HCID 27344312-Amino-4-methylpyridine-3-carboxylic acid

HCID 904122826-Amino-3-methylpicolinic acid

Product 1

HCID 90412569HCID 90412569, compound

Procedure

Prepared analogous to Example 82 substituting 6-amino-3-methylpicolinic acid with 2-amino-4-methylnicotinic acid.

Sources & evidence

ORD record: ord-839963dbab7d4bd0b0c3a0cc7e408218
Source dataset: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09062078B2

Reaction notes

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