Ethyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoate → Methyl 2-benzenesulphonylmethyl-5-bromobenzoate
Reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH2:20]C)=[O:18])=[C:15](OC)[C:14]([Br:24])=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.BrC1C=CC(CSC2C=CC=CC=2)=C(C=1)C(OC)=O>>[C:1]1([S:7]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([Br:24])=[CH:15][C:16]=2[C:17]([O:19][CH3:20])=[O:18])(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1Participants
3
Procedure
Prepared by proceeding in a similar manner to Intermediate 61, starting from methyl 5-bromo-2-(phenylthiomethyl)benzoate (Intermediate 78).
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-5a308c92e22d482faddace9d892d374a
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09067905B2
Reaction notes
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