Diisopropylamine → HCID 91139094, compound
Reaction equation
[CH:1]([NH:4][CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2].[CH3:8][C@@:9]12[O:19][C@H:18]1[C@@H:17]1[O:20][C@@H:16]1[C:15]1[C:21]([O:23][C@H:13]([CH:14]=1)[C@@H:12]1[C:24]([C:26]([O:28][C@H:11]1[CH2:10]2)=[O:27])=[CH2:25])=[O:22]>CC(C)=O>[CH:1]([N:4]([CH2:25][CH:24]1[CH:12]2[CH:11]([CH2:10][C:9]3([CH3:8])[CH:18]([CH:17]4[CH:16]([C:15]5[C:21](=[O:22])[O:23][CH:13]2[CH:14]=5)[O:20]4)[O:19]3)[O:28][C:26]1=[O:27])[CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Diisopropylamine (500 μmol; 70 μl) is added to a solution of mikanolide (100 μmol; 29 mg) in acetone (1 ml). The reaction mass is stirred for 30 minutes at ambient temperature then the solvent is eliminated by evaporation under reduced pressure. The residue is taken up in ether, filtered and dried under vacuum. 10 mg of product is obtained in the form of a white powder.