1,2,3,4-Tetrahydroisoquinoline → HCID 22484004, compound

Reaction equation

[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1.[Br:11][CH2:12][CH2:13][C:14](Cl)=[O:15]>>[Br:11][CH2:12][CH2:13][C:14]([N:2]1[CH2:3][CH2:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH2:1]1)=[O:15]

Participants

Reactant 2

HCID 70461,2,3,4-Tetrahydroisoquinoline

HCID 84944Propanoyl chloride, 3-bromo-

Product 1

HCID 22484004HCID 22484004, compound

Procedure

from 3,4-dihydro-1H-isoquinoline and 3-bromopropanoyl chloride

Sources & evidence

ORD record: ord-a03f0f1ee8304e0dbca6be38c14bf713
Source dataset: uspto-grants-2005_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06890916B2

Reaction notes

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