HCID 22482097, compound → HCID 22482102, compound
Reaction equation
[ClH:1].Cl.[CH3:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]([C:29]2[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[CH:31][CH:30]=2)[CH2:12][C:13]([N:15]2[CH2:20][CH2:19][N:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[O:27][CH3:28])[CH2:17][CH2:16]2)=O)=[CH:7][CH:6]=1.[N+](C1C=CC(C(C2C=CC([N+]([O-])=O)=CC=2)CC(N2CCN(C3C=CC=CC=3OC)CC2)=O)=CC=1)([O-])=O>>[ClH:1].[ClH:1].[CH3:36][O:35][C:32]1[CH:31]=[CH:30][C:29]([CH:11]([C:8]2[CH:9]=[CH:10][C:5]([O:4][CH3:3])=[CH:6][CH:7]=2)[CH2:12][CH2:13][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=3[O:27][CH3:28])[CH2:17][CH2:16]2)=[CH:34][CH:33]=1Participants
3
Procedure
This product was obtained in accordance with the procedure described above, (in Example 3b), with the sole exception that Compound 4A was employed here in place of Compound 3A. In addition, extraction was carried out here with ethyl acetate rather than chloroform. The obtained residue was dissolved in diethyl ether; then, after treatment with charcoal, the resultant solution was acidified with excess hydrochloric acid (3 N solution, in diethyl ether). After 3 h, the precipitate was recovered by filtration; the title product melted at 163-171° C.
Workup
- customThis product was obtained in accordance with the procedure
- extractionIn addition, extraction