3-Hydroxy-4-methylbenzoic acid → Benzoic acid, 3-methoxy-4-methyl-, methyl ester

Reaction equation

O[C:2]1C=C(C=CC=1C)C(O)=O.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[CH3:23])[C:17]([OH:19])=[O:18]>>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[CH3:23])[C:17]([O:19][CH3:2])=[O:18]

Participants

Reactant 2

HCID 685123-Hydroxy-4-methylbenzoic acid

HCID 815794-Methyl-m-anisic acid

Product 1

HCID 591123Benzoic acid, 3-methoxy-4-methyl-, methyl ester

Procedure

The process according to claim 1, wherein 3-hydroxy-4-methylbenzoic acid in the form of a mixture with 3-methoxy-4-methylbenzoic acid is reacted to give methyl 3-methoxy-4-methylbenzoate.

Workup

customis reacted

Sources & evidence

ORD record: ord-01c92b527d214239a9b01fdf57449386
Source dataset: uspto-grants-1995_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05424479

Reaction notes

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