HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dihydrocoumarin → N,N-diethyl-3-(2-hydroxyphenyl)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Product | N,N-diethyl-3-(2-hydroxyphenyl)propanamide | HCID 45803915 | 113.8% |
Reaction Steps
Diethylamine (98.5 g) and dihydrocoumarin (20.0 g) were refluxed for 4 hours. Excess diethylamine was removed in vacuo to leave 34.0 g of N,N-diethyl-3-(2-hydroxyphenyl) propionamide. 1H NMR (CDCl3): 7.26-7.03 (m, 2H), 6.91 (dd, 1H), 6.81 (td, 1H), 3.37 (quartet, 2H), 3.26 (quartet, 2H), 2.95 (m, 2H), 2.71 (m, 2H), 1.10 (quartet, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06399534B2 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-fa0321f61cef42a89d0c6a5c6af1d9ab |
| Source note | uspto-grants-2002_06 |