HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Propan-2-yl)pyridin-3-amine → 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Propan-2-yl)pyridin-3-amine | HCID 17854288 | — |
| Reactant | 5-Benzyloxy-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 17854502 | — |
| Product | 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 17854324 | 93.4% |
Reaction Steps
By the reaction and treatment in the same manner as in Preparation Example 18 using 5-benzyloxy-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.34 g) and 5-amino-2-isopropylpyridine (0.62 g) as starting materials, 5-benzyloxy-N-(6-isopropylpyridin-3-yl)-8-methyl-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.75 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-742264794409458aa408b142b51997a6 |
| Source note | uspto-grants-2012_06 |