HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic Acid → N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic Acid | HCID 10703469 | — |
| Reactant | N-((1-Ethyl-1H-pyrazol-4-yl)methyl)-4-isopropylaniline | HCID 21957909 | — |
| Product | N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 10181180 | 80.2% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.31 g) and [(1-ethylpyrazol-4-yl)methyl] (4-isopropylphenyl)amine (0.37 g) as starting materials, N-[(1-ethylpyrazol-4-yl)methyl]-N-(4-isopropylphenyl)-5-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.52 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-5d1128da2b9d481a9c4684aa693054cd |
| Source note | uspto-grants-2012_06 |