4-Bromo-2-methylaniline → 2-Methyl-4-(2-aminosulfonylphenyl)aniline

HRID 2186201

Reaction equation

HRID 2186201 reaction equation
F[C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([NH2:18])(=[O:17])=[O:16])[CH:6]=[CH:5][C:3]=1[NH2:4].[CH3:19]C1C=C(Br)C=CC=1N.FC1C=C(Br)C=CC=1N>>[CH3:19][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[S:15]([NH2:18])(=[O:17])=[O:16])[CH:6]=[CH:5][C:3]=1[NH2:4]

Participants

4

Reactant 3

HCID 114234-Bromo-2-methylanilineHCID 1230504-Bromo-2-fluoroanilineHCID 181773022-Fluoro-4-(2-aminosulfonylphenyl)aniline

Product 1

HCID 181773292-Methyl-4-(2-aminosulfonylphenyl)aniline

Procedure

This compound was prepared by the method described for 2-fluoro-4-(2-aminosulfonylphenyl)aniline described in EXAMPLE 8 by starting with 2-methyl-4-bromoaniline rather than 2-fluoro-4-bromoaniline.

Workup

  1. customThis compound was prepared by the method

Sources & evidence

ORD record
ord-d05acb640ff64d9e8cd8fc67f549f565
Source dataset
uspto-grants-2002_06
Patent number
US06403620B1

Linked notes

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