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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218944Generated: October 26, 2026

Exo-2-bornanamine → N-bicyclo[2.2.1]hept-2-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

https://huagongshe.com/reaction/218944

Reaction equation

Participants

RoleNameHCIDCharge
ReactantExo-2-bornanamineHCID 98480—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN-bicyclo[2.2.1]hept-2-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamideHCID 57649643—

Reaction Steps

N-bicyclo[2.2.1]hept-2-yl-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.31 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.45 mmol of bicyclo[2.2.1]hept-2-ylamine. LC/MS [10.01 min; 452 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198457B2
Source datasetuspto-grants-2012_06
ORD IDord-eb34e44a1e2e4dbaa589a7112b975b25
Source noteuspto-grants-2012_06