4-Methoxy-4-(3-hydroxy-trans-prop-1-enyl)tetrahydropyran → 4-Methoxy-4-(3-hydroxypropyl)tetrahydropyran
Reaction equation
[CH3:1][O:2][C:3]1(/[CH:9]=[CH:10]/[CH2:11][OH:12])[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>[Pd]>[CH3:1][O:2][C:3]1([CH2:9][CH2:10][CH2:11][OH:12])[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The desired compound is prepared by catalytic hydrogenolysis of 4-methoxy-4-(3-hydroxy-trans-prop-1-enyl) tetrahydropyran, prepared as in Example 1, steps 1-4, using palladium on calcium carbonate poisoned with lead according to the method of U.S. Pat. No. 5,268,379, Example 5.
Sources & evidence
- ORD record
- ord-4585bd61baae491283d6043f906b4cff
- Source dataset
- uspto-grants-1995_06
- Patent number
- US05426111
Reaction notes
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