2,6-Dichloro-4-iodopyridine → 2,2',6,6'-Tetrachloro-4,4'-bipyridine
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6](I)[CH:5]=[C:4]([Cl:9])[N:3]=1>[Cu]>[Cl:1][C:2]1[CH:7]=[C:6]([C:6]2[CH:5]=[C:4]([Cl:9])[N:3]=[C:2]([Cl:1])[CH:7]=2)[CH:5]=[C:4]([Cl:9])[N:3]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
a process of carrying out synthesis by stirring 2,6-dichloro-4-iodopyridine, listed as a starring material in Process (1-B), in the presence of a base by she catalysis of a copper catalyst such as copper powder with heating at 150° C. to 250° C. to yield 2,6,2′,6′-tetrachloro-[4,4′]bipyridyl, and treating this compound by the procedure of Process (B).
Workup
- customsynthesis
- temperaturewith heating at 150° C. to 250° C.
Sources & evidence
- ORD record
- ord-f118fd81b69a49bfa48e9b5c04cdd1f4
- Source dataset
- uspto-grants-2012_12
- Patent number
- US08324403B2
Reaction notes
Loading…