2-(2-Hydroxyethyl)pyridine → 3-(2-Pyridin-2-yl-ethoxy)-benzoic acid

Reaction equation

[OH:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1.O[C:11]1[CH:12]=[C:13]([CH:19]=[CH:20][CH:21]=1)[C:14]([O:16]CC)=[O:15]>>[N:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[CH2:3][CH2:2][O:1][C:11]1[CH:12]=[C:13]([CH:19]=[CH:20][CH:21]=1)[C:14]([OH:16])=[O:15]

Participants

Reactant 2

HCID 76752-(2-Hydroxyethyl)pyridine

HCID 24522Ethyl 3-hydroxybenzoate

Product 1

HCID 608929883-(2-Pyridin-2-yl-ethoxy)-benzoic acid

Procedure

Prepared from 2-(2-hydroxyethyl)pyridine and ethyl 3-hydroxybenzoate. LC-MS (m/z): 245 (M+1).

Sources & evidence

ORD record: ord-935f6ef078cd4ab3b2a3305171d2784b
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08334305B2

Reaction notes

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