3-Iodo-benzamidine → HCID 59254933, compound

Reaction equation

[Cl:1]C1C=C(C=C(I)C=1)C(N)=N.F[C:13]1[CH:21]=[CH:20][C:19]([I:22])=[CH:18][C:14]=1[C:15]([NH2:17])=[NH:16].IC1C=C(C=CC=1)C(N)=N>>[Cl:1][C:13]1[CH:21]=[CH:20][C:19]([I:22])=[CH:18][C:14]=1[C:15]([NH2:17])=[NH:16]

Participants

Reactant 3

HCID 35019453-Iodo-benzamidine

HCID 53417055HCID 53417055, compound

HCID 68601933HCID 68601933, compound

Product 1

HCID 59254933HCID 59254933, compound

Procedure

3-Chloro-5-iodo-benzamidine, 2-fluoro-5-iodo-benzamidine as well as 3-iodo-benzamidine may be prepared analogously.

Sources & evidence

ORD record: ord-23a6ddee1f8347fe85111a5a7a145113
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08334378B2

Reaction notes

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