2-Bromocyclododecanone → HCID 53838207, compound
Reaction equation
[CH2:1]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9](Br)[C:7](=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:15][O:16][C:17](=[O:23])[CH2:18][C:19]([O:21][CH3:22])=[O:20].[Na]>CO>[CH3:15][O:16][C:17](=[O:23])[CH:18]([CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]1=[O:8])[C:19]([O:21][CH3:22])=[O:20]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
reacting α-bromocyclododecanone with sodium malonic acid dimethyl ester in methanol at from about 10° to 40° C. to form 2-(2-oxocyclododec-1-yl)-malonic acid dimethyl ester;
Workup
- customat from about 10° to 40° C.
Sources & evidence
- ORD record
- ord-ea9d7da1b94f4775ae421caebf520754
- Source dataset
- uspto-grants-1982_11
- Patent number
- US04360468
Reaction notes
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