Benzotrichloride → Propanoyl chloride, 3-bromo-2,2,3,3-tetrafluoro-

HRID 2198960

Reaction equation

HRID 2198960 reaction equation
[Br:1][C:2]([F:10])([F:9])[C:3]([F:8])([F:7])[C:4](O)=[O:5].C1(C(Cl)(Cl)[Cl:18])C=CC=CC=1>>[Br:1][C:2]([F:10])([F:9])[C:3]([F:8])([F:7])[C:4]([Cl:18])=[O:5]

Participants

3

Reactant 2

HCID 7367BenzotrichlorideHCID 133289113-Bromo-2,2,3,3-tetrafluoropropanoic acid

Product 1

HCID 10490449Propanoyl chloride, 3-bromo-2,2,3,3-tetrafluoro-Yield 71%

Procedure

A mixture of 375.9 g (1.67 mol) of 3-bromotetrafluoropropionic acid, 10 g of ferric chloride, and 488.7 g (2.50 mol) of benzotrichloride was refluxed for 1.5 h, then crude product was removed, bp about 60°. Redistillation gave 287.9 g (71%) of 3-bromotetrafluoropropionyl chloride, bp 67°-68°. IR (CCl4): 5.53 (C=O). ##STR43##

Workup

  1. temperaturewas refluxed for 1.5 h
  2. customcrude product was removed
  3. distillationRedistillation

Sources & evidence

ORD record
ord-55ce83c957424924b2eb37fe082ca3bf
Source dataset
uspto-grants-1982_11
Patent number
US04360645

Linked notes

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