HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Propenoic acid, 3-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Glycidol | HCID 11164 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl isoferulate | HCID 6439893 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Propenoic acid, 3-phenyl- | HCID 8784 | — |
Reaction Steps
3 g of methyl isoferulate was dissolved in 600 ml of DMSO, and 370 mg of sodium hydride was added. The system was heated to 90° C. under N2 gas flow and 7 g of glycidol was added gradually. Heating and agitation was carried out for 0.5 hours. The system was cooled, neutralized by adding hydrochloric acid, solvent was removed and adduct of cinnamic acid and glycerin was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05426210 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-f297ae3acb9542e7bf85a53dda6a37d2 |
| Source note | uspto-grants-1995_06 |