4-Chlorobenzenesulfonyl chloride → 1-(2-(p-Chlorobenzenesulphonylamino)ethyl)naphthalene

HRID 22107Notes

Reaction equation

HRID 22107 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21](Cl)(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([NH:1][CH2:2][CH2:3][C:4]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[CH:7]=[CH:6][CH:5]=2)(=[O:23])=[O:22])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 208531-Naphthaleneethanamine

Product 1

HCID 150570151-(2-(p-Chlorobenzenesulphonylamino)ethyl)naphthalene

Procedure

Prepared from 1-(2-aminoethyl)naphthalene and 4-chlorobenzenesulphonic acid chloride analogously to Example 1a. The crude product was purified by column chromatography on silica gel using ethylene chloride/cyclohexane (2:1).

Workup

  1. customThe crude product was purified by column chromatography on silica gel

Sources & evidence

ORD record
ord-63effced1d994800bc9aeab5fb8189b3
Source dataset
uspto-grants-1995_06
Patent number
US05426119

Reaction notes

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