Thionyl Chloride → HCID 88422751, compound

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([CH3:14])[CH:13]=1)[CH2:5][CH:6]([OH:10])[C:7](O)=[O:8].S(Cl)([Cl:17])=O>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([CH3:14])[CH:13]=1)[CH2:5][CH:6]([OH:10])[C:7]([Cl:17])=[O:8]

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 19379351HCID 19379351, compound

Product 1

HCID 88422751HCID 88422751, compound

Procedure

3,5-Dimethyl benzyl glycolic acid (5.59 g) was cooled to 0° C. Thionyl chloride (5 ml) was added and the stirred solution was refluxed for 2 h. The solvent was removed in vacuo to afford 3,5-dimethyl benzyl glycolic acid chloride as an oil.

Workup

temperaturethe stirred solution was refluxed for 2 h
customThe solvent was removed in vacuo

Sources & evidence

ORD record: ord-dd92091af385400ca76de8145c5d9c4b
Source dataset: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05459270

Reaction notes

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