4-Chlorobenzenesulfonyl chloride → 2-(2-(p-Chlorobenzenesulphonylamino)ethyl)thiophene

HRID 22108

Reaction equation

[NH2:1][CH2:2][CH2:3][C:4]1[S:5][CH:6]=[CH:7][CH:8]=1.[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([S:16](Cl)(=[O:18])=[O:17])=[CH:12][CH:11]=1>>[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([S:16]([NH:1][CH2:2][CH2:3][C:4]2[S:5][CH:6]=[CH:7][CH:8]=2)(=[O:18])=[O:17])=[CH:12][CH:11]=1

Participants

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chloride

HCID 116521Thiopheneethanamine

Product 1

HCID 27322652-(2-(p-Chlorobenzenesulphonylamino)ethyl)thiophene

Procedure

Prepared from 2-(2-aminoethyl)-thiophene and 4-chlorobenzenesulphonic acid chloride analogously to Example 1a.

Sources & evidence

ORD record: ord-38bbc63114da45d4874ef48df39614a7
Source dataset: uspto-grants-1995_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05426119

Linked notes

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