(3-((Methylsulfonyl)amino)phenyl)acetic acid → HCID 68881619, compound

HRID 2212014

Reaction equation

HRID 2212014 reaction equation
[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@@H:10]([CH2:14][NH2:15])[CH2:9]2)=[CH:4][CH:3]=1.[CH3:16][S:17]([NH:20][C:21]1[CH:22]=[C:23]([CH2:27][C:28](O)=[O:29])[CH:24]=[CH:25][CH:26]=1)(=[O:19])=[O:18]>>[Cl:1][C:2]1[S:6][C:5]([CH2:7][N:8]2[CH2:13][CH2:12][O:11][C@@H:10]([CH2:14][NH:15][C:28](=[O:29])[CH2:27][C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][S:17]([CH3:16])(=[O:18])=[O:19])[CH:22]=3)[CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 2773885(3-((Methylsulfonyl)amino)phenyl)acetic acidHCID 68881347HCID 68881347, compound

Product 1

HCID 68881619HCID 68881619, compoundYield 55%

Procedure

Example 49 was prepared in an analogous manner to Example 44 using a mixture of Intermediate 14 (0.1 g) and Intermediate 18 (0.1 g) to give the title compound (0.102 g).

Workup

  1. customExample 49 was prepared in an analogous manner to Example 44 using

Sources & evidence

ORD record
ord-4f5330d8162c4f51a8c1a7c368cc70aa
Source dataset
uspto-grants-2006_09
Patent number
US07101882B2

Linked notes

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