Isoniazid → HCID 178444545, compound

HRID 221348Notes

Reaction equation

HRID 221348 reaction equation
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH2:11]([CH:16]1[CH2:21][CH2:20][CH:19]([C:22](O)=[O:23])[CH2:18][CH2:17]1)[CH2:12][CH2:13][CH2:14][CH3:15]>>[N:5]1[CH:6]=[CH:7][C:2]([C:1]([NH:9][NH:10][C:22]([C@H:19]2[CH2:20][CH2:21][C@H:16]([CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH2:17][CH2:18]2)=[O:23])=[O:8])=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 3767IsoniazidHCID 988824-Pentylcyclohexanecarboxylic Acid

Product 1

HCID 178444545HCID 178444545, compound

Procedure

Isonicotinic acid hydrazide was reacted with 4-pentylcyclohexane carboxylic acid in a similar fashion to that described in Preparation 16 to afford the title compound: RT=4.79 min; m/z (ES+)=318.0 [M+H]+.

Workup

  1. customthat described in Preparation 16

Sources & evidence

ORD record
ord-a3583c59ca884dd2bdbdc000661bf0cd
Source dataset
uspto-grants-2012_06
Patent number
US08207147B2

Reaction notes

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