Hydrazine → HCID 21947598, compound
Reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][N:12]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:4][CH:3]=1.NN>C(O)C>[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])=[CH:4][CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 2-4 (7.2 g, 24.5 mmol), hydrazine (3.8 mL), and ethanol (500 mL) was heated at reflux for 4 hours. The resulting mixture was cooled and filtered, and the filtrate concentrated to give 2-5 as a yellow solid (4.7 g) contaminated with some phthalhydrazide.
Workup
- temperaturewas heated
- temperatureat reflux for 4 hours
- temperatureThe resulting mixture was cooled
- filtrationfiltered
- concentrationthe filtrate concentrated
Sources & evidence
- ORD record
- ord-0f76b292b1834ee9a3cb1ea97addaf33
- Source dataset
- uspto-grants-2006_09
- Patent number
- US07109191B2
Reaction notes
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