HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R)-5'-bromo-3'H-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine] → (2'R)-5'-(Benzofuran-3-yl)spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R)-5'-bromo-3'H-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine] | HCID 54506690 | — |
| Reactant | 3-Tri-n-butylstannylbenzofuran | HCID 68615772 | — |
| Product | (2'R)-5'-(Benzofuran-3-yl)spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine] | HCID 10404519 | — |
Reaction Steps
Prepared by a method analogous to that described for the preparation of Example 4 from (2′R)-5′-bromospiro[1-azabicyclo[2.2.2]octane-3,2′(3′H)-furo[2,3-b]pyridine] and 3-tri-n-butylstannylbenzofuran. The title compound was obtained as a colourless solid; m/e 333 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07417049B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-d313a48f61d64c59a329a8ec918a6b31 |
| Source note | uspto-grants-2008_08 |