Ethanolamine → HCID 21947121, compound

Reaction equation

[CH3:1][CH:2]1[C:7]([CH:9]=[O:10])(C)[CH2:6][CH2:5][CH:4]=[CH:3]1.S([O-])([O-])(=O)=O.[Na+].[Na+].[CH2:18]([CH2:20][NH2:21])O.[CH3:22]O>>[CH3:1][CH:2]1[CH:3]=[C:4]([CH3:22])[CH2:5][CH2:6][CH:7]1[CH:9]1[NH:21][CH2:20][CH2:18][O:10]1

Participants

Reactant 4

HCID 700Ethanolamine

HCID 887Methanol

HCID 24436Sodium Sulfate

HCID 3034463TRIPLAL

Product 1

HCID 21947121HCID 21947121, compound

Procedure

To a 0° C. stirred solution of 66 g (0.47 mol) triplal and 21 g sodium sulfate in 150 mL of methanol is added 29 g (0.47 mol) of ethanolamine. The reaction is allowed to warm to room temperature. After stirring for 24 h the mixture is cooled to 0° C. and the solids are removed via vacuum filtration through Celite. Evaporation of the solvent gives a clear, slightly yellow oil.