HCID 178490558, compound → HCID 178490559, compound
Reaction equation
[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:9](=[O:25])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]([OH:22])=[O:21])=[C:14]([O:23][CH3:24])[CH:13]=2)[CH2:4][CH2:3]1>[C].[Pd].CO>[CH3:1][C@H:2]1[CH2:3][CH2:4][C@H:5]([NH:8][C:9](=[O:25])[CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]([OH:22])=[O:21])=[C:14]([O:23][CH3:24])[CH:13]=2)[CH2:6][CH2:7]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
Using 0.5 of N-(trans-4-methylcyclohexyl)-4-(carboxymethoxy)-3-methoxycinnamamide (Example 172), 0.025 g of 10% palladium-carbon, and 70 ml of methanol, a reaction similar to that conducted in Example 147 was carried out. As a result, 0.34 g of N-(trans-4-methylcyclohexyl) -3-[4-(carboxymethoxy)-3-methoxyphenyl]propionamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties: