HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 19927721, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| Reactant | 6-methoxy-7-(oxiranylmethoxy)-2H-1-benzopyran-2-one | HCID 19927717 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 19927721 | HCID 19927721 | 80% |
Reaction Steps
Method C (1.5 d at 45° C.); starting materials: 6-methoxy-7-(oxiranylmethoxy)-2H-1-benzopyran-2-one (example 86) and 1-(3-trifluoromethylphenyl)piperazine; yield 80%; fusion point 133°-135° C. (from methanol). Hydrochloride: method F; yield 83%; fusion point 125°-128° C. (decomposes; from isopropanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428038 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-6057111434ac468bbdef2a80a5866e2e |
| Source note | uspto-grants-1995_06 |