1-Chlorododecane → 3-Dimethylaminopropyl Laurate

HRID 223270

Reaction equation

HRID 223270 reaction equation
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][OH:6].[CH2:8](Cl)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].[OH-:21].[Na+]>C(Cl)(Cl)Cl>[N:2]([CH2:3][CH2:4][CH2:5][O:6][C:8]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[O:21])([CH3:7])[CH3:1]

Participants

5

Reactant 3

HCID 81921-ChlorododecaneHCID 14798Sodium HydroxideHCID 766463-(Dimethylamino)-1-propanol

Product 1

HCID 36130803-Dimethylaminopropyl Laurate

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In accordance with the procedure of Example 10, 72.2 g of 3-dimethylamino-1-propanol and 153.1 g of lauryl chloride are reacted in altogether 250 ml of CHCl3. The reaction mixture is neutralised with 147 ml of 20% NaOH. Yield: 157.2 g (82.1%) of product with a boiling point of 110° C./0.1 torr.

Sources & evidence

ORD record
ord-46d16faaa6464c50bf3707fe16399824
Source dataset
uspto-grants-1982_10
Patent number
US04352913

Linked notes

Loading…