3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid → 3,4-Dichloro-5-cyano-1H-pyrrole-2-carboxylic acid
Reaction equation
ClC1C(Cl)=C(C)NC=1C(O)=O.[Cl:12][C:13]1[C:17]([Cl:18])=[C:16]([C:19]#[N:20])[NH:15][C:14]=1[C:21]([O:23]C)=[O:22]>>[Cl:12][C:13]1[C:17]([Cl:18])=[C:16]([C:19]#[N:20])[NH:15][C:14]=1[C:21]([OH:23])=[O:22]Participants
3
Procedure
The title compound was prepared by a procedure analogous to Intermediate 3 starting from methyl 3,4-dichloro-5-cyano-1H-pyrrole-2-carboxy late (Intermediate 130).
Sources & evidence
- ORD record
- ord-af064eca6d45496eb81e119a7c8ee209
- Source dataset
- uspto-grants-2010_05
- Patent number
- US07709503B2
Reaction notes
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