Cyclopropaneethanamine → 3-(cyclopropylmethylamino)-N-methyl-propanamide

HRID 2234399Notes

Reaction equation

[CH:1]1([CH2:4]CN)C[CH2:2]1.C[CH:8]([NH:11][CH2:12][CH2:13][C:14]([NH:16][CH3:17])=[O:15])CC>>[CH:1]1([CH2:8][NH:11][CH2:12][CH2:13][C:14]([NH:16][CH3:17])=[O:15])[CH2:4][CH2:2]1

Participants

Reactant 2

HCID 10240761Cyclopropaneethanamine

HCID 467360473-(Sec-butylamino)-N-methylpropanamide

Product 1

HCID 618631993-(cyclopropylmethylamino)-N-methyl-propanamide

Procedure

Using 2-Cyclopropylethanamine—Aldrich and analogous conditions to Intermediate 89 the title compound was obtained as a pale yellow oil (590 mg)

Sources & evidence

ORD record: ord-9dd080cbb501495b94b42ab4d527f1b2
Source dataset: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07709471B2

Reaction notes

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