Hypochlorite → D-Arabinose

Participants

Reaction Steps

The hypochlorite solution is metered into the warm gluconate solution at a rate such that the addition is complete within a period of about 10-60 minutes, preferably about 30 minutes. The hypochlorite solution can, of course, also be metered in over a longer period, and this may be unavoidable in the case of very large batches. However, as a rule, the addition is effected in as short a time as possible. Thereafter, the mixture is stirred for a further brief period until the excess hypochlorite has disappeared. D-arabinose may then be isolated in a conventional manner. The yield of D-arabinose is about 70-75%, relative to the starting D-glucose, and this is achieved even when the crude fermentation solution from oxidation of D-glucose is employed.

Provenance & Evidence