HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl chloride → Methyl 4-methyl-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphtoylthio)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl chloride | HCID 2795466 | — |
| Reactant | Methyl 3-mercapto-4-methyl benzoate | HCID 13633551 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Methyl 4-methyl-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphtoylthio)benzoate | HCID 13633563 | 88.3% |
Reaction Steps
In a manner analogous to Example 1(a), starting with 1.83 g (10 mmol) of methyl 3-mercapto-4-methyl benzoate, 1.5 ml of triethylamine and 2.76 g (11 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphtoyl chloride, methyl 4-methyl-3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphtoylthio)-benzoate (3.50 g; 88%) is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428052 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-ce226f6565bb422a9d2595aa4ecabfee |
| Source note | uspto-grants-1995_06 |