Thionyl Chloride → p-Butoxybenzyl chloride

HRID 2241854Notes

Reaction equation

HRID 2241854 reaction equation
[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][C:7]([CH2:8][Cl:9])=[CH:6][CH:5]=1)[CH3:2].S(Cl)(Cl)=O.[CH2:16](OC1C=CC(CO)=CC=1)[CH2:17]CC>C(Cl)Cl>[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][C:7]([CH2:8][Cl:9])=[CH:6][CH:5]=1)[CH2:2][CH2:16][CH3:17]

Participants

5

Reactant 3

HCID 24386Thionyl ChlorideHCID 803464-ButoxybenzenemethanolHCID 20639711-(Chloromethyl)-4-Ethoxybenzene

Product 1

HCID 10012985p-Butoxybenzyl chloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Was synthesized following the same general procedure as that for the preparation of 4-ethoxybenzyl chloride; thionyl chloride (7.42 g, 69.2 mmol), 4-butoxybenzyl alcohol (9.45 g, 52.4 mmol), CH2Cl2 (145 mL).

Workup

  1. customWas synthesized

Sources & evidence

ORD record
ord-9bd1e1d60ac142fbbaacce3d10513730
Source dataset
uspto-grants-2010_03
Patent number
US07671033B2

Reaction notes

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