Methyl 2-isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate → Methyl 3-isopropyl-3',5'-dimethyl-4'-(2-oxopropoxy)biphenyl-4-carboxylate
Reaction equation
Br[C:2]1[CH:12]=[C:11]([CH3:13])[C:5]([O:6][CH2:7][C:8](=[O:10])[CH3:9])=[C:4]([CH3:14])[CH:3]=1.[CH:15]([C:18]1[CH:27]=[C:26](B2OC(C)(C)C(C)(C)O2)[CH:25]=[CH:24][C:19]=1[C:20]([O:22][CH3:23])=[O:21])([CH3:17])[CH3:16]>>[CH:15]([C:18]1[CH:27]=[C:26]([C:2]2[CH:12]=[C:11]([CH3:13])[C:5]([O:6][CH2:7][C:8](=[O:10])[CH3:9])=[C:4]([CH3:14])[CH:3]=2)[CH:25]=[CH:24][C:19]=1[C:20]([O:22][CH3:23])=[O:21])([CH3:17])[CH3:16]Participants
3
Procedure
The title compound was prepared according to procedures analogous to those as described in Reference Example 31 by using 1-(4-bromo-2,6-dimethylphenoxy)propan-2-one and methyl 2-isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate.
Sources & evidence
- ORD record
- ord-9727bc0c9c484943992f13f8863a32f8
- Source dataset
- uspto-grants-2010_03