Nitric Acid → Glucose-6-Phosphate

HRID 224741

Reaction equation

HRID 224741 reaction equation
[OH-].[Na+].[P:3]([O:7][CH2:8][C@@H:9]([OH:18])[C@@H:10]([OH:17])[C@H:11]([OH:16])[C@@H:12]([OH:15])[CH:13]=[O:14])([O-:6])([O-:5])=[O:4].[Na+].[Na+].[N+]([O-])(O)=O>O>[P:3]([O:7][CH2:8][C@@H:9]([OH:18])[C@@H:10]([OH:17])[C@H:11]([OH:16])[C@@H:12]([OH:15])[CH:13]=[O:14])([OH:5])([OH:6])=[O:4]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 14798Sodium HydroxideHCID 18594434d-glucose 6-phosphate disodium salt

Product 1

HCID 439958Glucose-6-Phosphate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To 22.5 ml of a 0.67 M aqueous solution of cis-[Pt(NH3)2 -(H2O)](NO3)2, the pH of which had been adjusted to 4 with sodium hydroxide, there was added 4.23 grams disodium D-glucose-6-phosphate dissolved in 30 ml of water. The pH of the reaction mixture was then adjusted to 5.0 using 2 M nitric acid. The solution was stoppered, and stirred for 42 days as in the previous examples. The above-identified, water-soluble blue complex was isolated by the method described in Example 1 in a yield of 2.69 grams.

Workup

  1. customstirred for 42 days as in the previous examples

Sources & evidence

ORD record
ord-b494f5c26b6646f58665b9032e6da9f1
Source dataset
uspto-grants-1980_11
Patent number
US04234499

Linked notes

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