2-Methyl-4-amino-5-aminomethylpyrimidine carbonate → 4-Amino-2-methyl-5-pyrimidinemethanamine

HRID 2248074

Reaction equation

HRID 2248074 reaction equation
C(=O)(O)O.[CH3:5][C:6]1[N:11]=[C:10]([NH2:12])[C:9]([CH2:13][NH2:14])=[CH:8][N:7]=1>C(O)(C)C>[CH3:5][C:6]1[N:11]=[C:10]([NH2:12])[C:9]([CH2:13][NH2:14])=[CH:8][N:7]=1

Participants

3

Reactant 1

HCID 179918792-Methyl-4-amino-5-aminomethylpyrimidine carbonate

Product 1

HCID 667624-Amino-2-methyl-5-pyrimidinemethanamine

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Conditions

Temperature
85 °C

Procedure

An amount of 170 g of isopropanol was added to 30.0 g of the 2-methyl-4-amino-5-aminomethylpyrimidine carbonate thus obtained, followed by heating at about 85° C. for 180 minutes to give 2-methyl-4-amino-5-aminomethylpyrimidine with purity of 99.0%.

Workup

  1. customthus obtained

Sources & evidence

ORD record
ord-a50f703487d34e34a96e06a641c77b92
Source dataset
uspto-grants-1991_08
Patent number
US05037982

Linked notes

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