N-acetyl-2-imidazolinone → 1-Acetyl-2(1,3,4-trimethyl-5-pyrazolyl) amino-2-imidazoline

Reaction equation

Cl.[NH2:2][C:3]1[N:7]([CH3:8])[N:6]=[C:5]([CH3:9])[C:4]=1[CH3:10].[C:11]([N:14]1[CH2:18][C:17](=O)[N:16]=[CH:15]1)(=[O:13])[CH3:12]>>[C:11]([N:14]1[CH2:18][CH2:17][N:16]=[C:15]1[NH:2][C:3]1[N:7]([CH3:8])[N:6]=[C:5]([CH3:9])[C:4]=1[CH3:10])(=[O:13])[CH3:12]

Participants

Reactant 2

HCID 22350258N-acetyl-2-imidazolinone

HCID 233305165-Amino-1,3,4-trimethyl pyrazole hydrochloride

Product 1

HCID 127637921-Acetyl-2(1,3,4-trimethyl-5-pyrazolyl) amino-2-imidazoline

Procedure

5-Amino-1,3,4-trimethyl pyrazole hydrochloride (8.00 g.) and 1-acetyl-2-imidazolinone (7.05 g.) were reacted as described in Example I to give 7.90 g. mp 212°-215° (crystallized from CH3CN)

Workup

customto give 7.90 g
custommp 212°-215° (crystallized from CH3CN)

Sources & evidence

ORD record: ord-593d2f3628694bc7aa18fcd8a9895f6b
Source dataset: uspto-grants-1980_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04234594

Reaction notes

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