Sulfuric Acid → Thiophene-2-thiol, S-acetyl-
Reaction equation
Cl[C:2]1[S:3][CH:4]=[CH:5][CH:6]=1.OC1[C:12](C)=[C:11]([O:14]C)[S:10]C=1C(OC)=O.S(=O)(=O)(O)O.C(O)(=S)C>C(O)(=O)C>[C:11]([S:10][C:2]1[S:3][CH:4]=[CH:5][CH:6]=1)(=[O:14])[CH3:12]Participants
6
Procedure
The chlorothiophene of (e) above (0.016 mol) in 10 ml of acetic acid was added to a solution of 0.9 ml of concentrated sulphuric acid in 10 ml of acetic acid. Whilst stirring, thioacetic acid (0.016 mol) was added and the mixture stood at room temperature for eight hours. Filtration of the precipitate afforded 75% of acetylthiothiophene which was recrystallised from hexane, m.p. 112°-114° C.
Workup
- filtrationFiltration of the precipitate
Sources & evidence
- ORD record
- ord-84c0e2b679d04790a398bf6f9fc5f9b5
- Source dataset
- uspto-grants-1991_08
- Patent number
- US05041461
Reaction notes
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