7-Methylbenzo[d]oxazole-2-carbonitrile → HCID 19994725, compound

Reaction equation

C(C1OC2C=C(C[Br:13])C=CC=2N=1)#N.[C:14]([C:16]1[O:17][C:18]2[C:24]([CH3:25])=[CH:23][CH:22]=[CH:21][C:19]=2[N:20]=1)#[N:15]>>[Br:13][CH2:25][C:24]1[C:18]2[O:17][C:16]([C:14]#[N:15])=[N:20][C:19]=2[CH:21]=[CH:22][CH:23]=1

Participants

Reactant 2

HCID 199946817-Methylbenzo[d]oxazole-2-carbonitrile

HCID 19994737HCID 19994737, compound

Product 1

HCID 19994725HCID 19994725, compound

Procedure

When the 2-cyano-6-bromomethylbenzoxazole in Example 10, Step 2 is replaced with 2-cyano-7-methylbenzoxazole, 7-bromomethyl-2-cyanobenzoxazole is obtained.

Sources & evidence

ORD record: ord-b2cae1945f1f461ea0d1a5425654db38
Source dataset: uspto-grants-1991_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05041453

Reaction notes

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